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ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation

Overview of attention for article published in Cell Communication and Signaling, January 2013
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Title
ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation
Published in
Cell Communication and Signaling, January 2013
DOI 10.1186/1478-811x-11-5
Pubmed ID
Authors

Karla LH Feijs, Henning Kleine, Anne Braczynski, Alexandra H Forst, Nicolas Herzog, Patricia Verheugd, Ulrike Linzen, Elisabeth Kremmer, Bernhard Lüscher

Abstract

Although ADP-ribosylation has been described five decades ago, only recently a distinction has been made between eukaryotic intracellular poly- and mono-ADP-ribosylating enzymes. Poly-ADP-ribosylation by ARTD1 (formerly PARP1) is best known for its role in DNA damage repair. Other polymer forming enzymes are ARTD2 (formerly PARP2), ARTD3 (formerly PARP3) and ARTD5/6 (formerly Tankyrase 1/2), the latter being involved in Wnt signaling and regulation of 3BP2. Thus several different functions of poly-ADP-ribosylation have been well described whereas intracellular mono-ADP-ribosylation is currently largely undefined. It is for example not known which proteins function as substrate for the different mono-ARTDs. This is partially due to lack of suitable reagents to study mono-ADP-ribosylation, which limits the current understanding of this post-translational modification.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
India 1 1%
Germany 1 1%
Unknown 78 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 23%
Researcher 13 16%
Student > Bachelor 11 14%
Student > Master 11 14%
Professor 4 5%
Other 10 12%
Unknown 13 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 28 35%
Biochemistry, Genetics and Molecular Biology 20 25%
Pharmacology, Toxicology and Pharmaceutical Science 6 7%
Chemistry 5 6%
Medicine and Dentistry 3 4%
Other 7 9%
Unknown 12 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2013.
All research outputs
#18,326,065
of 22,693,205 outputs
Outputs from Cell Communication and Signaling
#686
of 979 outputs
Outputs of similar age
#221,613
of 285,214 outputs
Outputs of similar age from Cell Communication and Signaling
#18
of 21 outputs
Altmetric has tracked 22,693,205 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 979 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
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We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.