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Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders

Overview of attention for article published in Molecular Brain, September 2016
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Title
Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders
Published in
Molecular Brain, September 2016
DOI 10.1186/s13041-016-0263-x
Pubmed ID
Authors

Alejandro Medrano-Fernández, Angel Barco

Abstract

The current view of neuroplasticity depicts the changes in the strength and number of synaptic connections as the main physical substrate for behavioral adaptation to new experiences in a changing environment. Although transcriptional regulation is known to play a role in these synaptic changes, the specific contribution of activity-induced changes to both the structure of the nucleus and the organization of the genome remains insufficiently characterized. Increasing evidence indicates that plasticity-related genes may work in coordination and share architectural and transcriptional machinery within discrete genomic foci. Here we review the molecular and cellular mechanisms through which neuronal nuclei structurally adapt to stimuli and discuss how the perturbation of these mechanisms can trigger behavioral malfunction.

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The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 108 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 30 28%
Researcher 18 17%
Student > Doctoral Student 8 7%
Student > Bachelor 7 6%
Student > Master 7 6%
Other 18 17%
Unknown 20 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 34 31%
Neuroscience 21 19%
Agricultural and Biological Sciences 19 18%
Medicine and Dentistry 4 4%
Psychology 3 3%
Other 6 6%
Unknown 21 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 November 2016.
All research outputs
#14,599,900
of 25,373,627 outputs
Outputs from Molecular Brain
#463
of 1,198 outputs
Outputs of similar age
#183,460
of 346,160 outputs
Outputs of similar age from Molecular Brain
#6
of 20 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,198 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 346,160 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.