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CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes

Overview of attention for article published in Retrovirology, July 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

news
1 news outlet
twitter
1 X user

Citations

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19 Dimensions

Readers on

mendeley
30 Mendeley
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Title
CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes
Published in
Retrovirology, July 2012
DOI 10.1186/1742-4690-9-62
Pubmed ID
Authors

Emmanuelle Wilhelm, Marie-Christine Doyle, Isaac Nzaramba, Alexandre Magdzinski, Nancy Dumais, Brendan Bell

Abstract

HIV latency is an obstacle for the eradication of HIV from infected individuals. Stable post-integration latency is controlled principally at the level of transcription. The HIV trans-activating protein, Tat, plays a key function in enhancing HIV transcriptional elongation. The HIV core promoter is specifically required for Tat-mediated trans-activation of HIV transcription. In addition, the HIV core promoter has been shown to be a potential anti-HIV drug target. Despite the pivotal role of the HIV core promoter in the control of HIV gene expression, the molecular mechanisms that couple Tat function specifically to the HIV core promoter remain unknown.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 2 7%
United States 1 3%
Unknown 27 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 40%
Student > Master 4 13%
Researcher 3 10%
Student > Bachelor 3 10%
Student > Doctoral Student 1 3%
Other 2 7%
Unknown 5 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 40%
Engineering 3 10%
Medicine and Dentistry 2 7%
Immunology and Microbiology 2 7%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 3 10%
Unknown 7 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2017.
All research outputs
#4,835,823
of 25,373,627 outputs
Outputs from Retrovirology
#227
of 1,273 outputs
Outputs of similar age
#32,442
of 178,780 outputs
Outputs of similar age from Retrovirology
#2
of 11 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,273 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,780 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.