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Sex, stress, and epigenetics: regulation of behavior in animal models of mood disorders

Overview of attention for article published in Biology of Sex Differences, January 2013
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (64th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

twitter
4 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
50 Dimensions

Readers on

mendeley
92 Mendeley
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Title
Sex, stress, and epigenetics: regulation of behavior in animal models of mood disorders
Published in
Biology of Sex Differences, January 2013
DOI 10.1186/2042-6410-4-1
Pubmed ID
Abstract

Women have a higher incidence of stress related disorders including depression and generalized anxiety disorder, and epigenetic mechanisms likely contribute to this sex difference. Evidence from preclinical research suggests that epigenetic mechanisms are responsible for both sexual dimorphism of brain regions and sensitivity of the stress response. Epigenetic modifications such as DNA methylation and histone modifications can occur transgenerationally, developmentally, or in response to environmental stimuli such as stress exposure. This review will provide an overview of the various forms of epigenetic modifications observed in the central nervous system and will explain how these mechanisms contribute to a sexually dimorphic brain. It will also discuss the ways in which epigenetic alterations coincide with, and functionally contribute to, the behavioral response to stress across the lifespan. Ultimately, this review will focus on novel research utilizing animal models to investigate sex differences in epigenetic mechanisms that influence susceptibility to stress. Exploration of this relationship reveals epigenetic mechanisms with the potential to explain sexual dimorphism in the occurrence of stress related disorders.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Argentina 1 1%
Canada 1 1%
Unknown 88 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 20%
Student > Master 15 16%
Student > Bachelor 15 16%
Researcher 10 11%
Student > Postgraduate 5 5%
Other 20 22%
Unknown 9 10%
Readers by discipline Count As %
Neuroscience 21 23%
Agricultural and Biological Sciences 21 23%
Medicine and Dentistry 13 14%
Psychology 13 14%
Biochemistry, Genetics and Molecular Biology 4 4%
Other 9 10%
Unknown 11 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 February 2013.
All research outputs
#1,500,447
of 3,616,025 outputs
Outputs from Biology of Sex Differences
#31
of 59 outputs
Outputs of similar age
#96,447
of 280,549 outputs
Outputs of similar age from Biology of Sex Differences
#4
of 10 outputs
Altmetric has tracked 3,616,025 research outputs across all sources so far. This one has received more attention than most of these and is in the 57th percentile.
So far Altmetric has tracked 59 research outputs from this source. They receive a mean Attention Score of 5.0. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,549 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.