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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Associations between BRAFV600E and prognostic factors and poor outcomes in papillary thyroid carcinoma: a meta-analysis
|
|---|---|
| Published in |
World Journal of Surgical Oncology, September 2016
|
| DOI | 10.1186/s12957-016-0979-1 |
| Pubmed ID | |
| Authors |
Chunping Liu, Tianwen Chen, Zeming Liu |
| Abstract |
The objective of this study is to perform a meta-analysis to evaluate the associations between the BRAF(V600E) mutation status and aggressive clinicopathological features and poor prognostic factors in papillary thyroid cancer. A literature search was performed within the PubMed, MEDLINE, Web of Science databases, and EMBASE databases using the Medical Subject Headings and keywords from January 2003 to July 2015. Individual study-specific odds ratios and confidence intervals were calculated, as were the Mantel-Haenszel pooled odds ratios for the combined studies. Sixty-three studies of 20,764 patients were included in the final analysis. Compared with wild-type BRAF, the BRAF(V600E) mutation was associated with aggressive clinicopathological factors, including extrathyroidal extension, higher TNM stage, lymph node metastasis, and recurrence, and was associated with reduced overall survival; however, there was no significant association between the presence of BRAF mutation and distant metastasis. BRAF mutations are closely associated with aggressive clinicopathological characteristics and poorer prognosis in papillary thyroid cancer. Accordingly, aggressive treatment should be considered for papillary thyroid cancer patients with BRAF mutation. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| China | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 1% |
| Unknown | 83 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 13 | 15% |
| Researcher | 11 | 13% |
| Student > Master | 7 | 8% |
| Student > Postgraduate | 5 | 6% |
| Professor | 4 | 5% |
| Other | 15 | 18% |
| Unknown | 29 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 31 | 37% |
| Biochemistry, Genetics and Molecular Biology | 8 | 10% |
| Computer Science | 2 | 2% |
| Agricultural and Biological Sciences | 2 | 2% |
| Nursing and Health Professions | 2 | 2% |
| Other | 7 | 8% |
| Unknown | 32 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2021.
All research outputs
#3,271,476
of 22,886,568 outputs
Outputs from World Journal of Surgical Oncology
#90
of 2,046 outputs
Outputs of similar age
#59,202
of 334,695 outputs
Outputs of similar age from World Journal of Surgical Oncology
#3
of 20 outputs
Altmetric has tracked 22,886,568 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,046 research outputs from this source. They receive a mean Attention Score of 2.1. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,695 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.