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Changes in red blood cell membrane structure in type 2 diabetes: a scanning electron and atomic force microscopy study

Overview of attention for article published in Cardiovascular Diabetology, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

blogs
1 blog
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3 X users

Citations

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157 Dimensions

Readers on

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183 Mendeley
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Title
Changes in red blood cell membrane structure in type 2 diabetes: a scanning electron and atomic force microscopy study
Published in
Cardiovascular Diabetology, January 2013
DOI 10.1186/1475-2840-12-25
Pubmed ID
Authors

Antoinette V Buys, Mia-Jean Van Rooy, Prashilla Soma, Dirk Van Papendorp, Boguslaw Lipinski, Etheresia Pretorius

Abstract

Red blood cells (RBCs) are highly deformable and possess a robust membrane that can withstand shear force. Previous research showed that in diabetic patients, there is a changed RBC ultrastructure, where these cells are elongated and twist around spontaneously formed fibrin fibers. These changes may impact erythrocyte function. Ultrastructural analysis of RBCs in inflammatory and degenerative diseases can no longer be ignored and should form a fundamental research tool in clinical studies. Consequently, we investigated the membrane roughness and ultrastructural changes in type 2 diabetes. Atomic force microscopy (AFM) was used to study membrane roughness and we correlate this with scanning electron microscopy (SEM) to compare results of both the techniques with the RBCs of healthy individuals. We show that the combined AFM and SEM analyses of RBCs give valuable information about the disease status of patients with diabetes. Effectiveness of treatment regimes on the integrity, cell shape and roughness of RBCs may be tracked, as this cell's health status is crucial to the overall wellness of the diabetic patient.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 183 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
France 1 <1%
Germany 1 <1%
Unknown 180 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 37 20%
Student > Master 25 14%
Researcher 23 13%
Student > Bachelor 22 12%
Student > Postgraduate 10 5%
Other 24 13%
Unknown 42 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 29 16%
Medicine and Dentistry 26 14%
Biochemistry, Genetics and Molecular Biology 21 11%
Physics and Astronomy 21 11%
Engineering 16 9%
Other 24 13%
Unknown 46 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2019.
All research outputs
#3,699,092
of 23,576,969 outputs
Outputs from Cardiovascular Diabetology
#258
of 1,467 outputs
Outputs of similar age
#38,989
of 285,870 outputs
Outputs of similar age from Cardiovascular Diabetology
#8
of 69 outputs
Altmetric has tracked 23,576,969 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,467 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.1. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 285,870 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.