Title |
Prospective European-wide multicentre study on a blood based real-time PCR for the diagnosis of acute schistosomiasis
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Published in |
BMC Infectious Diseases, January 2013
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DOI | 10.1186/1471-2334-13-55 |
Pubmed ID | |
Authors |
Dominic Wichmann, Sven Poppert, Heidrun Von Thien, Joannes Clerinx, Sebastian Dieckmann, Mogens Jensenius, Philippe Parola, Joachim Richter, Mirjam Schunk, August Stich, Philipp Zanger, Gerd D Burchard, Egbert Tannich |
Abstract |
Acute schistosomiasis constitutes a rare but serious condition in individuals experiencing their first prepatent Schistosoma infection. To circumvent costly and time-consuming diagnostics, an early and rapid diagnosis is required. So far, classic diagnostic tools such as parasite microscopy or serology lack considerable sensitivity at this early stage of Schistosoma infection. To validate the use of a blood based real-time polymerase chain reaction (PCR) test for the detection of Schistosoma DNA in patients with acute schistosomiasis who acquired their infection in various endemic regions we conducted a European-wide prospective study in 11 centres specialized in travel medicine and tropical medicine. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Venezuela, Bolivarian Republic of | 2 | 50% |
United Kingdom | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 70 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 15% |
Student > Ph. D. Student | 9 | 13% |
Student > Master | 9 | 13% |
Other | 5 | 7% |
Student > Doctoral Student | 5 | 7% |
Other | 17 | 24% |
Unknown | 16 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 23 | 32% |
Agricultural and Biological Sciences | 9 | 13% |
Biochemistry, Genetics and Molecular Biology | 9 | 13% |
Immunology and Microbiology | 4 | 6% |
Environmental Science | 3 | 4% |
Other | 6 | 8% |
Unknown | 18 | 25% |