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Clinical and pathological features of hepatoid carcinoma of the ovary

Overview of attention for article published in World Journal of Surgical Oncology, January 2013
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Title
Clinical and pathological features of hepatoid carcinoma of the ovary
Published in
World Journal of Surgical Oncology, January 2013
DOI 10.1186/1477-7819-11-29
Pubmed ID
Authors

Lina Wang, Yanping Zhong, Lingling Sun, Heng Zhou, Wei Chen, Xiaoxia Zhang

Abstract

Hepatoid carcinoma of the ovary (HCO), a rare invasive malignant tumor composed mainly of epithelioid cells, presented with unilateral or bilateral ovarian masses and elevated serum α-fetoprotein (AFP), has been found mainly in post-menopausal women. We hereby report on the case of a 53-year-old Chinese woman who presented with abdominal distension and a lower abdominal mass with high serum levels of CA-125 and AFP. She was later diagnosed with bilateral HCO. After surgery and following chemotherapy, the patient had no recurrence of tumor or ascites. The hepatoid cells were positive for AFP, p53 and CK7 by immunohistochemistry. Her serum CA-125 and AFP levels had decreased significantly after surgery. Our results suggest that testing and monitoring of serum levels of AFP and CA-125 are considered as potential biomarkers in the diagnosis and progression of this malignancy, and that tissue immunohistochemical staining for AFP, p53 and CK7, plays an important role in distinguishing HCO from other ovarian tumors.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 6%
Unknown 15 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 19%
Student > Master 3 19%
Student > Ph. D. Student 2 13%
Librarian 2 13%
Student > Bachelor 1 6%
Other 0 0%
Unknown 5 31%
Readers by discipline Count As %
Medicine and Dentistry 7 44%
Agricultural and Biological Sciences 1 6%
Mathematics 1 6%
Physics and Astronomy 1 6%
Engineering 1 6%
Other 0 0%
Unknown 5 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2013.
All research outputs
#20,180,477
of 22,694,633 outputs
Outputs from World Journal of Surgical Oncology
#1,588
of 2,039 outputs
Outputs of similar age
#249,226
of 282,145 outputs
Outputs of similar age from World Journal of Surgical Oncology
#80
of 82 outputs
Altmetric has tracked 22,694,633 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,039 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 82 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.