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Inability to detect significant absorption of immunoreactive soya protein in healthy adults may be relevant to its weak allergenicity

Overview of attention for article published in Clinical and Translational Allergy, February 2013
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Title
Inability to detect significant absorption of immunoreactive soya protein in healthy adults may be relevant to its weak allergenicity
Published in
Clinical and Translational Allergy, February 2013
DOI 10.1186/2045-7022-3-6
Pubmed ID
Authors

Cecilia M Lund, Christina G Dirks, Mona H Pedersen, Bettina M Jensen, Lars K Poulsen

Abstract

Soya and peanut are botanically closely related and share cross-reacting antigens, but compared to soya, peanut allergy has a higher prevalence with more severe allergic reactions. Furthermore, the threshold dose for eliciting reactions is higher for soya. A difference in undigested protein absorption between the two foods, might explain this diversity.In the current study the amount of soya protein absorbed after soya bean ingestion in healthy adults was estimated. Ten subjects ingested 100 grams of soya beans (40 grams of soya protein) and blood was drawn before and 1, 3 and 24 hours after administration. Serum was analysed by ELISA and histamine release (HR). In all serum samples the soya protein concentration was below quantification limit (1.6 ng/ml which corresponds to 4.8 μg or 0.12 parts per million absorbed soya protein.We could not detect any significant absorption of soya protein. While we cannot totally exlude technical reasons, it may also reflect a true poor absorption in healthy adult volunteers. This could, in turn, be relevant to the apparently weak allergenicity of soy protein by comparison with peanut protein in allergic subjects.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 20%
Student > Master 2 13%
Other 1 7%
Lecturer 1 7%
Lecturer > Senior Lecturer 1 7%
Other 3 20%
Unknown 4 27%
Readers by discipline Count As %
Medicine and Dentistry 6 40%
Agricultural and Biological Sciences 2 13%
Immunology and Microbiology 2 13%
Engineering 1 7%
Unknown 4 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2013.
All research outputs
#17,286,379
of 25,374,917 outputs
Outputs from Clinical and Translational Allergy
#600
of 756 outputs
Outputs of similar age
#194,085
of 291,554 outputs
Outputs of similar age from Clinical and Translational Allergy
#6
of 6 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 756 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 291,554 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.