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Noninvasive in-vivo tracing and imaging of transplanted stem cells for liver regeneration

Overview of attention for article published in Stem Cell Research & Therapy, September 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

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2 X users
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1 patent
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1 Facebook page

Citations

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17 Dimensions

Readers on

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50 Mendeley
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Title
Noninvasive in-vivo tracing and imaging of transplanted stem cells for liver regeneration
Published in
Stem Cell Research & Therapy, September 2016
DOI 10.1186/s13287-016-0396-y
Pubmed ID
Authors

Panpan Cen, Jiajia Chen, Chenxia Hu, Linxiao Fan, Jie Wang, Lanjuan Li

Abstract

Terminal liver disease is a major cause of death globally. The only ultimate therapeutic approach is orthotopic liver transplant. Because of the innate defects of organ transplantation, stem cell-based therapy has emerged as an effective alternative, based on the capacity of stem cells for multilineage differentiation and their homing to injured sites. However, the disease etiology, cell type, timing of cellular graft, therapeutic dose, delivery route, and choice of endpoints have varied between studies, leading to different, even divergent, results. In-vivo cell imaging could therefore help us better understand the fate and behaviors of stem cells to optimize cell-based therapy for liver regeneration. The primary imaging techniques in preclinical or clinical studies have consisted of optical imaging, magnetic resonance imaging, radionuclide imaging, reporter gene imaging, and Y chromosome-based fluorescence in-situ hybridization imaging. More attention has been focused on developing new or modified imaging methods for longitudinal and high-efficiency tracing. Herein, we provide a descriptive overview of imaging modalities and discuss recent advances in the field of molecular imaging of intrahepatic stem cell grafts.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 49 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 28%
Researcher 6 12%
Student > Master 5 10%
Student > Bachelor 4 8%
Student > Postgraduate 3 6%
Other 11 22%
Unknown 7 14%
Readers by discipline Count As %
Medicine and Dentistry 14 28%
Biochemistry, Genetics and Molecular Biology 8 16%
Agricultural and Biological Sciences 7 14%
Engineering 6 12%
Neuroscience 2 4%
Other 5 10%
Unknown 8 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 June 2018.
All research outputs
#6,309,205
of 22,890,496 outputs
Outputs from Stem Cell Research & Therapy
#606
of 2,426 outputs
Outputs of similar age
#96,893
of 321,668 outputs
Outputs of similar age from Stem Cell Research & Therapy
#11
of 41 outputs
Altmetric has tracked 22,890,496 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 2,426 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,668 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.