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Ethanol inhibits LPS-induced signaling and modulates cytokine production in peritoneal macrophages in vivo in a model for binge drinking

Overview of attention for article published in BMC Immunology, January 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)

Mentioned by

blogs
1 blog

Citations

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16 Dimensions

Readers on

mendeley
32 Mendeley
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Title
Ethanol inhibits LPS-induced signaling and modulates cytokine production in peritoneal macrophages in vivo in a model for binge drinking
Published in
BMC Immunology, January 2009
DOI 10.1186/1471-2172-10-49
Pubmed ID
Authors

Stephen B Pruett, Ruping Fan

Abstract

Previous reports indicate that ethanol, in a binge drinking model in mice, inhibits the production of pro-inflammatory cytokines in vivo. However, the inhibition of signaling through TLR4 has not been investigated in this experimental model in vivo. Considering evidence that signaling can be very different in vitro and in vivo, the present study was conducted to determine if effects of ethanol on TLR4 signaling reported for cells in culture or cells removed from ethanol treated mice and stimulated in culture also occur when ethanol treatment and TLR4 activation occur in vivo.

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
Chile 1 3%
United States 1 3%
Unknown 29 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 28%
Student > Bachelor 8 25%
Student > Ph. D. Student 5 16%
Student > Master 3 9%
Other 2 6%
Other 3 9%
Unknown 2 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 34%
Medicine and Dentistry 8 25%
Biochemistry, Genetics and Molecular Biology 3 9%
Immunology and Microbiology 1 3%
Earth and Planetary Sciences 1 3%
Other 3 9%
Unknown 5 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2013.
All research outputs
#3,989,512
of 19,943,904 outputs
Outputs from BMC Immunology
#60
of 539 outputs
Outputs of similar age
#50,103
of 268,673 outputs
Outputs of similar age from BMC Immunology
#1
of 3 outputs
Altmetric has tracked 19,943,904 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 539 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,673 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them