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Ovine reference materials and assays for prion genetic testing

Overview of attention for article published in BMC Veterinary Research, April 2010
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Title
Ovine reference materials and assays for prion genetic testing
Published in
BMC Veterinary Research, April 2010
DOI 10.1186/1746-6148-6-23
Pubmed ID
Authors

Michael P Heaton, Kreg A Leymaster, Theodore S Kalbfleisch, Brad A Freking, Timothy PL Smith, Michael L Clawson, William W Laegreid

Abstract

Genetic predisposition to scrapie in sheep is associated with several variations in the peptide sequence of the prion protein gene (PRNP). DNA-based tests for scoring PRNP codons are essential tools for eradicating scrapie and for evaluating rare alleles for increased resistance to disease. In addition to those associated with scrapie, there are dozens more PRNP polymorphisms that may occur in various flocks. If not accounted for, these sites may cause base-pair mismatching with oligonucleotides used in DNA testing. Thus, the fidelity of scrapie genetic testing is enhanced by knowing the position and frequency of PRNP polymorphisms in targeted flocks.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 31%
Student > Ph. D. Student 4 15%
Student > Doctoral Student 2 8%
Student > Bachelor 2 8%
Other 2 8%
Other 3 12%
Unknown 5 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 42%
Biochemistry, Genetics and Molecular Biology 4 15%
Medicine and Dentistry 2 8%
Immunology and Microbiology 1 4%
Veterinary Science and Veterinary Medicine 1 4%
Other 2 8%
Unknown 5 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2015.
All research outputs
#14,782,490
of 25,371,288 outputs
Outputs from BMC Veterinary Research
#927
of 3,297 outputs
Outputs of similar age
#82,463
of 104,467 outputs
Outputs of similar age from BMC Veterinary Research
#4
of 4 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,297 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,467 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.