Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation

Overview of attention for article published in Journal of Neuroinflammation, March 2018

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@EricTopol @research_long @polybioRF @microbeminded2 @rddysum @LukeMMoney @R_H_Ebright @DrEricDing @Nature @WesElyMD @alisonannyoung @VirusesImmunity @ArisKatzourakis @c_drosten @MarionKoopmans @edwardcholmes @WHO @DrTedros https://t.co/u60GfUcbek

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@elray67 @fitterhappierAJ @PeacockFlu @Luke87358261 @MonicaGandhi9 @VirusesImmunity @stuartjdneil And Tat…

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“ApoE4 was the least potent and effective at preventing HIV-1 Tat internalization and at decreasing Tat-mediated HIV-1 LTR transactivation.” https://t.co/yRRjh3LHUq “potentiated by an ApoE4 structure modulator that changes ApoE4 into an ApoE3-like phenotyp

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