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Sodium vanadate combined with l-ascorbic acid delays disease progression, enhances motor performance, and ameliorates muscle atrophy and weakness in mice with spinal muscular atrophy

Overview of attention for article published in BMC Medicine, February 2013
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39 Mendeley
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Title
Sodium vanadate combined with l-ascorbic acid delays disease progression, enhances motor performance, and ameliorates muscle atrophy and weakness in mice with spinal muscular atrophy
Published in
BMC Medicine, February 2013
DOI 10.1186/1741-7015-11-38
Pubmed ID
Authors

Huei-Chun Liu, Chen-Hung Ting, Hsin-Lan Wen, Li-Kai Tsai, Hsiu-Mei Hsieh-Li, Hung Li, Sue Lin-Chao

Abstract

Proximal spinal muscular atrophy (SMA), a neurodegenerative disorder that causes infant mortality, has no effective treatment. Sodium vanadate has shown potential for the treatment of SMA; however, vanadate-induced toxicity in vivo remains an obstacle for its clinical application. We evaluated the therapeutic potential of sodium vanadate combined with a vanadium detoxification agent, L-ascorbic acid, in a SMA mouse model.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 21%
Student > Ph. D. Student 8 21%
Researcher 6 15%
Other 4 10%
Student > Bachelor 4 10%
Other 3 8%
Unknown 6 15%
Readers by discipline Count As %
Medicine and Dentistry 12 31%
Biochemistry, Genetics and Molecular Biology 5 13%
Neuroscience 3 8%
Agricultural and Biological Sciences 3 8%
Psychology 3 8%
Other 7 18%
Unknown 6 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2013.
All research outputs
#12,557,761
of 22,696,971 outputs
Outputs from BMC Medicine
#2,644
of 3,403 outputs
Outputs of similar age
#151,931
of 287,569 outputs
Outputs of similar age from BMC Medicine
#78
of 86 outputs
Altmetric has tracked 22,696,971 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,403 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.5. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,569 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.