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Defective alterations in the collagen network to prostacyclin in COPD lung fibroblasts

Overview of attention for article published in Respiratory Research, February 2013
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Mentioned by

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1 X user
googleplus
1 Google+ user

Citations

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22 Dimensions

Readers on

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26 Mendeley
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Title
Defective alterations in the collagen network to prostacyclin in COPD lung fibroblasts
Published in
Respiratory Research, February 2013
DOI 10.1186/1465-9921-14-21
Pubmed ID
Authors

Anna-Karin Larsson-Callerfelt, Oskar Hallgren, Annika Andersson-Sjöland, Lena Thiman, Johan Björklund, Josefine Kron, Kristian Nihlberg, Leif Bjermer, Claes-Göran Löfdahl, Gunilla Westergren-Thorsson

Abstract

Prostacyclin analogs are potent vasodilators and possess anti-inflammatory properties. However, the effect of prostacyclin on extracellular matrix (ECM) in COPD is not well known. Collagen fibrils and proteoglycans are essential ECM components in the lung and fibroblasts are key players in regulating the homeostasis of ECM proteins. The aim was to study the synthesis of prostacyclin and its effect on fibroblast activity and ECM production, and in particular collagen I and the collagen-associated proteoglycans biglycan and decorin.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 27%
Student > Bachelor 5 19%
Student > Master 3 12%
Researcher 2 8%
Student > Postgraduate 2 8%
Other 4 15%
Unknown 3 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 27%
Biochemistry, Genetics and Molecular Biology 4 15%
Medicine and Dentistry 4 15%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Immunology and Microbiology 1 4%
Other 4 15%
Unknown 5 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2013.
All research outputs
#16,048,009
of 25,374,917 outputs
Outputs from Respiratory Research
#1,891
of 3,062 outputs
Outputs of similar age
#183,079
of 296,603 outputs
Outputs of similar age from Respiratory Research
#16
of 30 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 296,603 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.