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Non-Pain-Related CRF1 Activation in the Amygdala Facilitates Synaptic Transmission and Pain Responses

Overview of attention for article published in Molecular Pain, January 2013
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Mentioned by

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2 tweeters

Citations

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66 Dimensions

Readers on

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63 Mendeley
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Title
Non-Pain-Related CRF1 Activation in the Amygdala Facilitates Synaptic Transmission and Pain Responses
Published in
Molecular Pain, January 2013
DOI 10.1186/1744-8069-9-2
Pubmed ID
Authors

Guangchen Ji, Yu Fu, Hita Adwanikar, Volker Neugebauer

Abstract

Corticotropin-releasing factor (CRF) plays an important role in affective states and disorders. CRF is not only a "stress hormone" but also a neuromodulator outside the hypothalamic-pituitary-adrenocortical (HPA) axis. The amygdala, a brain center for emotions, is a major site of extrahypothalamic expression of CRF and its G-protein-coupled receptors. Our previous studies showed that endogenous activation of CRF1 receptors in an arthritis pain model contributes to amygdala hyperactivity and pain-related behaviors. Here we examined the synaptic and behavioral effects of CRF in the amygdala of normal animals in the absence of tissue injury or disease.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
France 1 2%
Unknown 61 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 24%
Student > Bachelor 12 19%
Researcher 8 13%
Student > Master 7 11%
Professor 7 11%
Other 11 17%
Unknown 3 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 27%
Medicine and Dentistry 16 25%
Neuroscience 14 22%
Psychology 6 10%
Biochemistry, Genetics and Molecular Biology 3 5%
Other 3 5%
Unknown 4 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2013.
All research outputs
#7,875,904
of 12,552,259 outputs
Outputs from Molecular Pain
#238
of 464 outputs
Outputs of similar age
#150,202
of 279,912 outputs
Outputs of similar age from Molecular Pain
#5
of 7 outputs
Altmetric has tracked 12,552,259 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 464 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,912 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.