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Fluid responsiveness prediction using Vigileo FloTrac measured cardiac output changes during passive leg raise test

Overview of attention for article published in Journal of Intensive Care, October 2016
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Title
Fluid responsiveness prediction using Vigileo FloTrac measured cardiac output changes during passive leg raise test
Published in
Journal of Intensive Care, October 2016
DOI 10.1186/s40560-016-0188-6
Pubmed ID
Authors

Anton Krige, Martin Bland, Thomas Fanshawe

Abstract

Passive leg raising (PLR) is a so called self-volume challenge used to test for fluid responsiveness. Changes in cardiac output (CO) or stroke volume (SV) measured during PLR are used to predict the need for subsequent fluid loading. This requires a device that can measure CO changes rapidly. The Vigileo™ monitor, using third-generation software, allows continuous CO monitoring. The aim of this study was to compare changes in CO (measured with the Vigileo device) during a PLR manoeuvre to calculate the accuracy for predicting fluid responsiveness. This is a prospective study in a 20-bedded mixed general critical care unit in a large non-university regional referral hospital. Fluid responders were defined as having an increase in CO of greater than 15 % following a fluid challenge. Patients meeting the criteria for circulatory shock with a Vigileo™ monitor (Vigileo™; FloTrac; Edwards™; Lifesciences, Irvine, CA, USA) already in situ, and assessed as requiring volume expansion by the clinical team based on clinical criteria, were included. All patients underwent a PLR manoeuvre followed by a fluid challenge. Data was collected and analysed on stroke volume variation (SVV) at baseline and CO and SVV changes during the PLR manoeuvre and following a subsequent fluid challenge in 33 patients. The majority had septic shock. Patient characteristics, baseline haemodynamic variables and baseline vasoactive infusion requirements were similar between fluid responders (10 patients) and non-responders (23 patients). Peak increase in CO occurred within 120 s during the PLR in all cases. Using an optimal cut point of 9 % increase in CO during the PLR produced an area under the receiver operating characteristic curve of 0.85 (95 % CI 0.63 to 1.00) with a sensitivity of 80 % (95 % CI 44 to 96 %) and a specificity of 91 % (95 % CI 70 to 98 %). CO changes measured by the Vigileo™ monitor using third-generation software during a PLR test predict fluid responsiveness in mixed medical and surgical patients with vasopressor-dependent circulatory shock.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 62 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 17%
Other 9 14%
Student > Ph. D. Student 8 13%
Student > Master 8 13%
Student > Postgraduate 6 10%
Other 11 17%
Unknown 10 16%
Readers by discipline Count As %
Medicine and Dentistry 38 60%
Nursing and Health Professions 7 11%
Business, Management and Accounting 2 3%
Immunology and Microbiology 1 2%
Neuroscience 1 2%
Other 0 0%
Unknown 14 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 October 2016.
All research outputs
#17,395,400
of 25,522,520 outputs
Outputs from Journal of Intensive Care
#458
of 580 outputs
Outputs of similar age
#212,794
of 327,548 outputs
Outputs of similar age from Journal of Intensive Care
#8
of 9 outputs
Altmetric has tracked 25,522,520 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 580 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.9. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
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We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one.