Title |
Multilevel omic data integration in cancer cell lines: advanced annotation and emergent properties
|
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Published in |
BMC Systems Biology, February 2013
|
DOI | 10.1186/1752-0509-7-14 |
Pubmed ID | |
Authors |
Yuanhua Liu, Valentina Devescovi, Suning Chen, Christine Nardini |
Abstract |
High-throughput (omic) data have become more widespread in both quantity and frequency of use, thanks to technological advances, lower costs and higher precision. Consequently, computational scientists are confronted by two parallel challenges: on one side, the design of efficient methods to interpret each of these data in their own right (gene expression signatures, protein markers, etc.) and, on the other side, realization of a novel, pressing request from the biological field to design methodologies that allow for these data to be interpreted as a whole, i.e. not only as the union of relevant molecules in each of these layers, but as a complex molecular signature containing proteins, mRNAs and miRNAs, all of which must be directly associated in the results of analyses that are able to capture inter-layers connections and complexity. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 20% |
Peru | 1 | 20% |
Germany | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 40% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Science communicators (journalists, bloggers, editors) | 1 | 20% |
Members of the public | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Sweden | 2 | 2% |
Italy | 1 | <1% |
Germany | 1 | <1% |
United Kingdom | 1 | <1% |
Canada | 1 | <1% |
Iran, Islamic Republic of | 1 | <1% |
Argentina | 1 | <1% |
Spain | 1 | <1% |
Unknown | 119 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 39 | 30% |
Researcher | 32 | 25% |
Student > Master | 10 | 8% |
Other | 9 | 7% |
Professor > Associate Professor | 7 | 5% |
Other | 17 | 13% |
Unknown | 14 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 40 | 31% |
Biochemistry, Genetics and Molecular Biology | 26 | 20% |
Computer Science | 14 | 11% |
Medicine and Dentistry | 9 | 7% |
Mathematics | 7 | 5% |
Other | 13 | 10% |
Unknown | 19 | 15% |