Title |
Murine norovirus infection does not cause major disruptions in the murine intestinal microbiota
|
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Published in |
Microbiome, February 2013
|
DOI | 10.1186/2049-2618-1-7 |
Pubmed ID | |
Authors |
Adam M Nelson, Michael D Elftman, Amelia K Pinto, Megan Baldridge, Patrick Hooper, Justin Kuczynski, Joseph F Petrosino, Vincent B Young, Christiane E Wobus |
Abstract |
Murine norovirus (MNV) is the most common gastrointestinal pathogen of research mice and can alter research outcomes in biomedical mouse models of inflammatory bowel disease (IBD). Despite indications that an altered microbiota is a risk factor for IBD, the response of the murine intestinal microbiota to MNV infection has not been examined. Microbiota disruption caused by MNV infection could introduce the confounding effects observed in research experiments. Therefore, this study investigated the effects of MNV infection on the intestinal microbiota of wild-type mice. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | 3% |
Unknown | 68 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 17 | 24% |
Student > Ph. D. Student | 15 | 21% |
Student > Master | 8 | 11% |
Professor | 6 | 9% |
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Other | 9 | 13% |
Unknown | 12 | 17% |
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Biochemistry, Genetics and Molecular Biology | 5 | 7% |
Veterinary Science and Veterinary Medicine | 3 | 4% |
Other | 3 | 4% |
Unknown | 14 | 20% |