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Citrus aurantium L. essential oil exhibits anxiolytic-like activity mediated by 5-HT1A-receptors and reduces cholesterol after repeated oral treatment

Overview of attention for article published in BMC Complementary Medicine and Therapies, February 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
1 news outlet
twitter
12 X users
facebook
19 Facebook pages
wikipedia
1 Wikipedia page
googleplus
1 Google+ user

Citations

dimensions_citation
85 Dimensions

Readers on

mendeley
130 Mendeley
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Title
Citrus aurantium L. essential oil exhibits anxiolytic-like activity mediated by 5-HT1A-receptors and reduces cholesterol after repeated oral treatment
Published in
BMC Complementary Medicine and Therapies, February 2013
DOI 10.1186/1472-6882-13-42
Pubmed ID
Authors

Celso A R A Costa, Thaís C Cury, Bruna O Cassettari, Regina K Takahira, Jorge C Flório, Mirtes Costa

Abstract

The current treatments for anxiety disorders and depression have multiple adverse effects in addition to a delayed onset of action, which has prompted efforts to find new substances with potential activity in these disorders. Citrus aurantium was chosen based on ethnopharmacological data because traditional medicine refers to the Citrus genus as useful in diminishing the symptoms of anxiety or insomnia, and C. aurantium has more recently been proposed as an adjuvant for antidepressants. In the present work, we investigated the biological activity underlying the anxiolytic and antidepressant effects of C. aurantium essential oil (EO), the putative mechanism of the anxiolytic-like effect, and the neurochemical changes in specific brain structures of mice after acute treatment. We also monitored the mice for possible signs of toxicity after a 14-day treatment.

X Demographics

X Demographics

The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 130 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 <1%
Unknown 129 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 16 12%
Student > Master 15 12%
Student > Ph. D. Student 13 10%
Researcher 11 8%
Student > Doctoral Student 11 8%
Other 28 22%
Unknown 36 28%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 25 19%
Agricultural and Biological Sciences 19 15%
Medicine and Dentistry 13 10%
Nursing and Health Professions 6 5%
Veterinary Science and Veterinary Medicine 4 3%
Other 21 16%
Unknown 42 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 January 2023.
All research outputs
#1,191,619
of 23,477,147 outputs
Outputs from BMC Complementary Medicine and Therapies
#182
of 3,693 outputs
Outputs of similar age
#9,204
of 195,139 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#3
of 66 outputs
Altmetric has tracked 23,477,147 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,693 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,139 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.