Whole genome sequencing has been routinely used in TB diagnostics in the UK. This paper discusses the advantages and limitations, especially for the identification of isoniazid resistance. #BMCInfectDis https://t.co/F88TPlFozV https://t.co/aTLh5yhUBr
RT @sanghyuk_shin: Evaluating the clinical impact of routine whole genome sequencing in #tuberculosis treatment decisions and the issue of…
Evaluating the clinical impact of routine whole genome sequencing in tuberculosis treatment decisions and the issue of isoniazid mono-resistance https://t.co/KbrAVsIgTM https://t.co/GKrm3Ajg9r
"WGS clearly has a substantial role in our routine UK clinical settings.. However, the majority of treatment changes defined by WGS were related to isoniazid resistance and given the 1 month TAT for WGS, it would be preferable to identify isoniazid resista