Title |
In-depth performance evaluation of PFP and ESG sequence-based function prediction methods in CAFA 2011 experiment
|
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Published in |
BMC Bioinformatics, February 2013
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DOI | 10.1186/1471-2105-14-s3-s2 |
Pubmed ID | |
Authors |
Meghana Chitale, Ishita K Khan, Daisuke Kihara |
Abstract |
Many Automatic Function Prediction (AFP) methods were developed to cope with an increasing growth of the number of gene sequences that are available from high throughput sequencing experiments. To support the development of AFP methods, it is essential to have community wide experiments for evaluating performance of existing AFP methods. Critical Assessment of Function Annotation (CAFA) is one such community experiment. The meeting of CAFA was held as a Special Interest Group (SIG) meeting at the Intelligent Systems in Molecular Biology (ISMB) conference in 2011. Here, we perform a detailed analysis of two sequence-based function prediction methods, PFP and ESG, which were developed in our lab, using the predictions submitted to CAFA. |
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