Title |
Chinese medicines as a resource for liver fibrosis treatment
|
---|---|
Published in |
Chinese Medicine, August 2009
|
DOI | 10.1186/1749-8546-4-16 |
Pubmed ID | |
Authors |
Yibin Feng, Kwok-Fan Cheung, Ning Wang, Ping Liu, Tadashi Nagamatsu, Yao Tong |
Abstract |
Liver fibrosis is a condition of abnormal proliferation of connective tissue due to various types of chronic liver injury often caused by viral infection and chemicals. Effective therapies against liver fibrosis are still limited. In this review, we focus on research on Chinese medicines against liver fibrosis in three categories, namely pure compounds, composite formulae and combination treatment using single compounds with composite formulae or conventional medicines. Action mechanisms of the anti-fibrosis Chinese medicines, clinical application, herbal adverse events and quality control are also reviewed. Evidence indicates that some Chinese medicines are clinically effective on liver fibrosis. Strict quality control such as research to identify and monitor the manufacturing of Chinese medicines enables reliable pharmacological, clinical and in-depth mechanism studies. Further experiments and clinical trials should be carried out on the platforms that conform to international standards. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 1 | 2% |
Chile | 1 | 2% |
Australia | 1 | 2% |
India | 1 | 2% |
Denmark | 1 | 2% |
Unknown | 40 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 24% |
Student > Ph. D. Student | 9 | 20% |
Student > Doctoral Student | 6 | 13% |
Researcher | 5 | 11% |
Student > Postgraduate | 3 | 7% |
Other | 7 | 16% |
Unknown | 4 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 36% |
Agricultural and Biological Sciences | 13 | 29% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 7% |
Computer Science | 1 | 2% |
Other | 4 | 9% |
Unknown | 5 | 11% |