Pleomorphic xanthoastrocytoma in the multiverse of epigenomics: is it time to recognize the variants?

@CraigHorbinski @NeuroOnc @BrainTumorInst @NeurosurgeryNM @NU_Pathology @TheUSCAP @LurieCancer @neuropathology So probably we must broaden our morphological understanding and recognize its variants… https://t.co/NraEjPNmpA

A great kind of madness! 🧙🏽‍♂️✨ Probably an under-recognised entity, as a few might have been misdiagnosed based on H&E only. Circumscription on imaging, focal spindle cell areas, CDKN2A/B homozygous deletion, MAPK pathway alterations and MC PXA are k

A letter to the editor commenting the morphological diversity of the methylation class “Pleomorphic Xanthoastrocytoma”. And for the title, a parallel with… take a look! Because we are geek pathologists! https://t.co/dYRpJV5ZMw #neuropathology @MarvelBR

RT @NeuropathClinic: Pleomorphic xanthoastrocytoma in the multiverse of epigenomics: is it time to recognize the variants? #neuropath http…