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The role of Cysteine 6.47 in class A GPCRs

Overview of attention for article published in BMC Molecular and Cell Biology, March 2013
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Title
The role of Cysteine 6.47 in class A GPCRs
Published in
BMC Molecular and Cell Biology, March 2013
DOI 10.1186/1472-6807-13-3
Pubmed ID
Authors

Mireia Olivella, Gianluigi Caltabiano, Arnau Cordomí

Abstract

The CWxP motif of transmembrane helix 6 (x: any residue) is highly conserved in class A GPCRs. Within this motif, W6.48 is a big star in the theory of the global "toggle switch" because of its key role in the activation mechanism of GPCRs upon ligand binding. With all footlights focused on W6.48, the reason why the preceding residue, C6.47, is largely conserved is still unknown. The present study is aimed to fill up this lack of knowledge by characterizing the role of C6.47 of the CWxP motif.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 2%
Brazil 1 1%
Unknown 80 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 22%
Student > Master 17 20%
Student > Bachelor 10 12%
Researcher 8 10%
Student > Doctoral Student 4 5%
Other 13 16%
Unknown 13 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 30 36%
Agricultural and Biological Sciences 17 20%
Chemistry 10 12%
Pharmacology, Toxicology and Pharmaceutical Science 6 7%
Computer Science 2 2%
Other 6 7%
Unknown 12 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2023.
All research outputs
#19,945,185
of 25,374,917 outputs
Outputs from BMC Molecular and Cell Biology
#896
of 1,233 outputs
Outputs of similar age
#155,065
of 209,695 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#17
of 23 outputs
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So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.