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Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors

Overview of attention for article published in Journal of Translational Medicine, March 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

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4 X users
patent
6 patents
wikipedia
1 Wikipedia page

Citations

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71 Dimensions

Readers on

mendeley
93 Mendeley
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Title
Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors
Published in
Journal of Translational Medicine, March 2013
DOI 10.1186/1479-5876-11-62
Pubmed ID
Authors

Claudia Marcela Diaz, Alberto Chiappori, Luigi Aurisicchio, Ansuman Bagchi, Jason Clark, Sheri Dubey, Arthur Fridman, Jesus C Fabregas, John Marshall, Elisa Scarselli, Nicola La Monica, Gennaro Ciliberto, Alberto J Montero

Abstract

DNA electroporation has been demonstrated in preclinical models to be a promising strategy to improve cancer immunity, especially when combined with other genetic vaccines in heterologous prime-boost protocols. We report the results of 2 multicenter phase 1 trials involving adult cancer patients (n=33) with stage II-IV disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 1%
Unknown 92 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 20%
Student > Ph. D. Student 15 16%
Student > Master 10 11%
Student > Bachelor 8 9%
Student > Postgraduate 6 6%
Other 17 18%
Unknown 18 19%
Readers by discipline Count As %
Medicine and Dentistry 20 22%
Biochemistry, Genetics and Molecular Biology 16 17%
Agricultural and Biological Sciences 11 12%
Immunology and Microbiology 9 10%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Other 13 14%
Unknown 19 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2021.
All research outputs
#2,574,843
of 22,701,287 outputs
Outputs from Journal of Translational Medicine
#404
of 3,969 outputs
Outputs of similar age
#22,073
of 195,228 outputs
Outputs of similar age from Journal of Translational Medicine
#8
of 60 outputs
Altmetric has tracked 22,701,287 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,969 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,228 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.