Title |
Evaluation of Entamoeba histolytica recombinant phosphoglucomutase protein for serodiagnosis of amoebic liver abscess
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Published in |
BMC Infectious Diseases, March 2013
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DOI | 10.1186/1471-2334-13-144 |
Pubmed ID | |
Authors |
Tan Zi Ning, Wong Weng Kin, Rahmah Noordin, See Too Wei Cun, Foo Phiaw Chong, Zeehaida Mohamed, Alfonso Olivos-Garcia, Lim Boon Huat |
Abstract |
Amoebic liver abscess (ALA) is the most frequent clinical presentation of extra-intestinal amoebiasis. The diagnosis of ALA is typically based on the developing clinical symptoms, characteristic changes on radiological imaging and serology. Numerous serological tests have been introduced for the diagnosis of ALA, either detecting circulating amoebic antigens or antibodies. However those tests show some pitfalls in their efficacy and/or the preparation of the tests are costly and tedious. The commercial IHA kit that used crude antigen was reported to be useful in diagnosis of ALA, however high antibody background in endemic areas may cause problems in its interpretation. Thus, discovery of well-defined antigen(s) is urgently needed to improve the weaknesses of current serodiagnostic tests. |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Germany | 1 | 3% |
Unknown | 29 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 8 | 27% |
Student > Ph. D. Student | 4 | 13% |
Student > Doctoral Student | 3 | 10% |
Other | 3 | 10% |
Researcher | 3 | 10% |
Other | 6 | 20% |
Unknown | 3 | 10% |
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Medicine and Dentistry | 6 | 20% |
Biochemistry, Genetics and Molecular Biology | 5 | 17% |
Environmental Science | 2 | 7% |
Immunology and Microbiology | 1 | 3% |
Other | 3 | 10% |
Unknown | 6 | 20% |