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Efficient production of chimeric mice from embryonic stem cells injected into 4- to 8-cell and blastocyst embryos

Overview of attention for article published in Journal of Animal Science and Biotechnology, March 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

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1 X user
facebook
1 Facebook page
wikipedia
1 Wikipedia page

Citations

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17 Dimensions

Readers on

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39 Mendeley
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Title
Efficient production of chimeric mice from embryonic stem cells injected into 4- to 8-cell and blastocyst embryos
Published in
Journal of Animal Science and Biotechnology, March 2013
DOI 10.1186/2049-1891-4-12
Pubmed ID
Authors

Minhua Hu, Hengxi Wei, Jingfeng Zhang, Yinshan Bai, Fenglei Gao, Li Li, Shouquan Zhang

Abstract

Production of chimeric mice is a useful tool for the elucidation of gene function. After successful isolation of embryonic stem (ES) cell lines, there are many methods for producing chimeras, including co-culture with the embryos, microinjection of the ES cells into pre-implantation embryos, and use of tetraploid embryos to generate the full ES-derived transgenic mice. Here, we aimed to generate the transgenic ES cell line, compare the production efficiency of chimeric mice and its proportion to yield the male chimeric mice by microinjected ES cells into 4- to 8-cell and blastocysts embryos with the application of Piezo-Micromanipulator (PMM), and trace the fate of the injected ES cells.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Portugal 1 3%
Switzerland 1 3%
Unknown 36 92%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 23%
Student > Ph. D. Student 7 18%
Researcher 5 13%
Student > Bachelor 2 5%
Student > Postgraduate 2 5%
Other 3 8%
Unknown 11 28%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 38%
Biochemistry, Genetics and Molecular Biology 8 21%
Medicine and Dentistry 3 8%
Immunology and Microbiology 1 3%
Engineering 1 3%
Other 0 0%
Unknown 11 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2023.
All research outputs
#7,205,295
of 25,374,647 outputs
Outputs from Journal of Animal Science and Biotechnology
#123
of 903 outputs
Outputs of similar age
#58,042
of 210,398 outputs
Outputs of similar age from Journal of Animal Science and Biotechnology
#2
of 6 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 903 research outputs from this source. They receive a mean Attention Score of 3.3. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,398 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.