Title |
Changes in bone marrow lesions in response to weight-loss in obese knee osteoarthritis patients: a prospective cohort study
|
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Published in |
BMC Musculoskeletal Disorders, March 2013
|
DOI | 10.1186/1471-2474-14-106 |
Pubmed ID | |
Authors |
Henrik Gudbergsen, Mikael Boesen, Robin Christensen, Else Marie Bartels, Marius Henriksen, Bente Danneskiold-Samsøe, Henning Bliddal |
Abstract |
Patients are susceptible for knee osteoarthritis (KOA) with increasing age and obesity and KOA is expected to become a major disabling disease in the future. An important feature of KOA on magnetic resonance imaging (MRI) is changes in the subchondral bone, bone marrow lesions (BMLs), which are related to the future degeneration of the knee joint as well as prevalent clinical symptoms. The aim of this study was to investigate the changes in BMLs after a 16-week weight-loss period in obese subjects with KOA and relate changes in BMLs to the effects of weight-loss on clinical symptoms. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 3% |
Unknown | 78 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 13 | 16% |
Researcher | 12 | 15% |
Student > Bachelor | 9 | 11% |
Student > Ph. D. Student | 7 | 9% |
Student > Postgraduate | 5 | 6% |
Other | 11 | 14% |
Unknown | 23 | 29% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 27 | 34% |
Nursing and Health Professions | 5 | 6% |
Agricultural and Biological Sciences | 5 | 6% |
Psychology | 3 | 4% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Other | 5 | 6% |
Unknown | 33 | 41% |