You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Pervasive sequence patents cover the entire human genome
|
|---|---|
| Published in |
Genome Medicine, March 2013
|
| DOI | 10.1186/gm431 |
| Pubmed ID | |
| Authors |
Jeffrey A Rosenfeld, Christopher E Mason |
| Abstract |
The scope and eligibility of patents for genetic sequences have been debated for decades, but a critical case regarding gene patents (Association of Molecular Pathologists v. Myriad Genetics) is now reaching the US Supreme Court. Recent court rulings have supported the assertion that such patents can provide intellectual property rights on sequences as small as 15 nucleotides (15mers), but an analysis of all current US patent claims and the human genome presented here shows that 15mer sequences from all human genes match at least one other gene. The average gene matches 364 other genes as 15mers; the breast-cancer-associated gene BRCA1 has 15mers matching at least 689 other genes. Longer sequences (1,000 bp) still showed extensive cross-gene matches. Furthermore, 15mer-length claims from bovine and other animal patents could also claim as much as 84% of the genes in the human genome. In addition, when we expanded our analysis to full-length patent claims on DNA from all US patents to date, we found that 41% of the genes in the human genome have been claimed. Thus, current patents for both short and long nucleotide sequences are extraordinarily non-specific and create an uncertain, problematic liability for genomic medicine, especially in regard to targeted re-sequencing and other sequence diagnostic assays. |
X Demographics
The data shown below were collected from the profiles of 141 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 37 | 26% |
| United Kingdom | 14 | 10% |
| Netherlands | 8 | 6% |
| France | 6 | 4% |
| Canada | 4 | 3% |
| Spain | 3 | 2% |
| Italy | 3 | 2% |
| Australia | 3 | 2% |
| Japan | 2 | 1% |
| Other | 16 | 11% |
| Unknown | 45 | 32% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 79 | 56% |
| Scientists | 52 | 37% |
| Science communicators (journalists, bloggers, editors) | 8 | 6% |
| Practitioners (doctors, other healthcare professionals) | 2 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 6% |
| Switzerland | 1 | 2% |
| Sweden | 1 | 2% |
| Denmark | 1 | 2% |
| Peru | 1 | 2% |
| Japan | 1 | 2% |
| Luxembourg | 1 | 2% |
| Unknown | 38 | 81% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 28% |
| Student > Ph. D. Student | 8 | 17% |
| Other | 6 | 13% |
| Professor > Associate Professor | 6 | 13% |
| Student > Bachelor | 2 | 4% |
| Other | 7 | 15% |
| Unknown | 5 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 20 | 43% |
| Medicine and Dentistry | 7 | 15% |
| Biochemistry, Genetics and Molecular Biology | 5 | 11% |
| Social Sciences | 3 | 6% |
| Computer Science | 2 | 4% |
| Other | 4 | 9% |
| Unknown | 6 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 253. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2023.
All research outputs
#147,169
of 25,582,611 outputs
Outputs from Genome Medicine
#25
of 1,597 outputs
Outputs of similar age
#870
of 210,684 outputs
Outputs of similar age from Genome Medicine
#2
of 24 outputs
Altmetric has tracked 25,582,611 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,597 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.7. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,684 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.