Report for: A dynamic network of transcription in LPS-treated human subjects.

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Title	A dynamic network of transcription in LPS-treated human subjects.
Published in	BMC Systems Biology, January 2009
DOI	10.1186/1752-0509-3-78
Pubmed ID	19638230
Authors	Junhee Seok, Wenzhong Xiao, Lyle L Moldawer, Ronald W Davis, Markus W Covert
Abstract	Understanding the transcriptional regulatory networks that map out the coordinated dynamic responses of signaling proteins, transcription factors and target genes over time would represent a significant advance in the application of genome wide expression analysis. The primary challenge is monitoring transcription factor activities over time, which is not yet available at the large scale. Instead, there have been several developments to estimate activities computationally. For example, Network Component Analysis (NCA) is an approach that can predict transcription factor activities over time as well as the relative regulatory influence of factors on each target gene.

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Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
Spain	1	2%
United States	1	2%
Netherlands	1	2%
Unknown	48	94%

Demographic breakdown

Readers by professional status	Count	As %
Researcher	17	33%
Student > Ph. D. Student	15	29%
Professor > Associate Professor	5	10%
Other	4	8%
Student > Postgraduate	3	6%
Other	6	12%
Unknown	1	2%

Readers by discipline	Count	As %
Agricultural and Biological Sciences	22	43%
Medicine and Dentistry	8	16%
Engineering	4	8%
Immunology and Microbiology	4	8%
Biochemistry, Genetics and Molecular Biology	4	8%
Other	6	12%
Unknown	3	6%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2010.

All research outputs

#2,017,509

of 3,628,259 outputs

Outputs from BMC Systems Biology

#277

of 595 outputs

Outputs of similar age

#1,477,477

of 2,726,505 outputs

Outputs of similar age from BMC Systems Biology

#261

of 575 outputs

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So far Altmetric has tracked 595 research outputs from this source. They receive a mean Attention Score of 2.6. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.

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A dynamic network of transcription in LPS-treated human subjects.

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Geographical breakdown

Demographic breakdown

Attention Score in Context