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Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing

Overview of attention for article published in Genome Medicine, March 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

blogs
5 blogs
policy
1 policy source
twitter
112 X users
patent
4 patents
facebook
3 Facebook pages
googleplus
2 Google+ users

Citations

dimensions_citation
384 Dimensions

Readers on

mendeley
782 Mendeley
citeulike
14 CiteULike
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Title
Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing
Published in
Genome Medicine, March 2013
DOI 10.1186/gm432
Pubmed ID
Authors

Jason O'Rawe, Tao Jiang, Guangqing Sun, Yiyang Wu, Wei Wang, Jingchu Hu, Paul Bodily, Lifeng Tian, Hakon Hakonarson, W Evan Johnson, Zhi Wei, Kai Wang, Gholson J Lyon

Abstract

To facilitate the clinical implementation of genomic medicine by next-generation sequencing, it will be critically important to obtain accurate and consistent variant calls on personal genomes. Multiple software tools for variant calling are available, but it is unclear how comparable these tools are or what their relative merits in real-world scenarios might be.

X Demographics

X Demographics

The data shown below were collected from the profiles of 112 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 782 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 34 4%
Germany 7 <1%
United Kingdom 7 <1%
Italy 5 <1%
France 4 <1%
Netherlands 4 <1%
Brazil 3 <1%
Switzerland 3 <1%
New Zealand 3 <1%
Other 25 3%
Unknown 687 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 251 32%
Student > Ph. D. Student 186 24%
Student > Master 80 10%
Other 48 6%
Professor > Associate Professor 41 5%
Other 107 14%
Unknown 69 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 361 46%
Biochemistry, Genetics and Molecular Biology 153 20%
Computer Science 72 9%
Medicine and Dentistry 57 7%
Engineering 10 1%
Other 42 5%
Unknown 87 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 111. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2023.
All research outputs
#383,746
of 25,837,817 outputs
Outputs from Genome Medicine
#62
of 1,611 outputs
Outputs of similar age
#2,510
of 212,550 outputs
Outputs of similar age from Genome Medicine
#2
of 24 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,611 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.7. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 212,550 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.