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Sex-specific risk of cardiovascular disease and cognitive decline: pregnancy and menopause

Overview of attention for article published in Biology of Sex Differences, March 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)

Mentioned by

news
1 news outlet
twitter
9 tweeters

Citations

dimensions_citation
37 Dimensions

Readers on

mendeley
49 Mendeley
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Title
Sex-specific risk of cardiovascular disease and cognitive decline: pregnancy and menopause
Published in
Biology of Sex Differences, March 2013
DOI 10.1186/2042-6410-4-6
Pubmed ID
Authors

Virginia M Miller, Vesna D Garovic, Kejal Kantarci, Jill N Barnes, Muthuvel Jayachandran, Michelle M Mielke, Michael J Joyner, Lynne T Shuster, Walter A Rocca

Abstract

Understanding the biology of sex differences is integral to personalized medicine. Cardiovascular disease and cognitive decline are two related conditions, with distinct sex differences in morbidity and clinical manifestations, response to treatments, and mortality. Although mortality from all-cause cardiovascular diseases has declined in women over the past five years, due in part to increased educational campaigns regarding the recognition of symptoms and application of treatment guidelines, the mortality in women still exceeds that of men. The physiological basis for these differences requires further research, with particular attention to two physiological conditions which are unique to women and associated with hormonal changes: pregnancy and menopause. Both conditions have the potential to impact life-long cardiovascular risk, including cerebrovascular function and cognition in women. This review draws on epidemiological, translational, clinical, and basic science studies to assess the impact of hypertensive pregnancy disorders on cardiovascular disease and cognitive function later in life, and examines the effects of post-menopausal hormone treatments on cardiovascular risk and cognition in midlife women. We suggest that hypertensive pregnancy disorders and menopause activate vascular components, i.e., vascular endothelium and blood elements, including platelets and leukocytes, to release cell-membrane derived microvesicles that are potential mediators of changes in cerebral blood flow, and may ultimately affect cognition in women as they age. Research into specific sex differences for these disease processes with attention to an individual's sex chromosomal complement and hormonal status is important and timely.

Twitter Demographics

The data shown below were collected from the profiles of 9 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 49 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 24%
Researcher 6 12%
Student > Master 6 12%
Student > Bachelor 4 8%
Student > Postgraduate 3 6%
Other 8 16%
Unknown 10 20%
Readers by discipline Count As %
Medicine and Dentistry 15 31%
Neuroscience 5 10%
Biochemistry, Genetics and Molecular Biology 4 8%
Psychology 3 6%
Computer Science 3 6%
Other 7 14%
Unknown 12 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 July 2014.
All research outputs
#1,810,502
of 18,833,065 outputs
Outputs from Biology of Sex Differences
#67
of 373 outputs
Outputs of similar age
#16,444
of 166,892 outputs
Outputs of similar age from Biology of Sex Differences
#1
of 2 outputs
Altmetric has tracked 18,833,065 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 373 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.5. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,892 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them