Emphasis on the Role of PF4 in the Incidence, Pathophysiology and Treatment of Heparin Induced Thrombocytopenia

RT @BagaiDr: Heparin Induced Thrombocytopenia (HIT) is caused by antibodies that recognize platelet factor 4 (PF4) associated with polyanio…

Heparin Induced Thrombocytopenia (HIT) is caused by antibodies that recognize platelet factor 4 (PF4) associated with polyanionic glycosaminoglycan drugs or displayed on vascular cell membranes. https://t.co/QQ0OqG9Pcg

Depending on the patient population, HIT occurs in 0.5-5% of patients receiving heparin for 5 or more days. Of patients with HIT, 30-72% develop thrombotic complications with 10% risk of limb amputation and 20-30% risk of death [7]. https://t.co/ssmchDfwMR

occurs in 0.5-5% of patients receiving heparin for 5 or more days. https://t.co/ssmchDfwMR