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Supplementation of carnitine leads to an activation of the IGF-1/PI3K/Akt signalling pathway and down regulates the E3 ligase MuRF1 in skeletal muscle of rats

Overview of attention for article published in Nutrition & Metabolism, March 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)

Mentioned by

twitter
5 tweeters
facebook
2 Facebook pages
video
2 video uploaders

Citations

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27 Dimensions

Readers on

mendeley
37 Mendeley
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Title
Supplementation of carnitine leads to an activation of the IGF-1/PI3K/Akt signalling pathway and down regulates the E3 ligase MuRF1 in skeletal muscle of rats
Published in
Nutrition & Metabolism, March 2013
DOI 10.1186/1743-7075-10-28
Pubmed ID
Authors

Janine Keller, Aline Couturier, Melanie Haferkamp, Erika Most, Klaus Eder

Abstract

Recently, it has been shown that carnitine down-regulates genes involved in the ubiquitin-proteasome system (UPS) in muscle of pigs and rats. The mechanisms underlying this observation are yet unknown. Based on the previous finding that carnitine increases plasma IGF-1 concentration, we investigated the hypothesis that carnitine down-regulates genes of the UPS by modulation of the of the IGF-1/PI3K/Akt signalling pathway which is an important regulator of UPS activity in muscle.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 5%
South Africa 1 3%
Japan 1 3%
Unknown 33 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 16%
Student > Ph. D. Student 6 16%
Student > Doctoral Student 4 11%
Professor 4 11%
Other 4 11%
Other 10 27%
Unknown 3 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 30%
Medicine and Dentistry 7 19%
Biochemistry, Genetics and Molecular Biology 5 14%
Pharmacology, Toxicology and Pharmaceutical Science 3 8%
Nursing and Health Professions 1 3%
Other 4 11%
Unknown 6 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2020.
All research outputs
#5,716,077
of 18,873,384 outputs
Outputs from Nutrition & Metabolism
#396
of 859 outputs
Outputs of similar age
#48,810
of 167,807 outputs
Outputs of similar age from Nutrition & Metabolism
#1
of 1 outputs
Altmetric has tracked 18,873,384 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 859 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.7. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,807 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them