Overestimation of benefit when clinical trials stop early: a simulation study

RT @guhjy: @drjohnm To keep the absolute relative risk reduction overestimate below 5%, 250 events were required in trials stopped early fo…

@drjohnm To keep the absolute relative risk reduction overestimate below 5%, 250 events were required in trials stopped early for benefit. https://t.co/Lc2usBe3yL

RT @GuyattGH: Latest just published simulation confirms large effect overestimates of trials stopped early for benefit. Trials typical of…

RT @GuyattGH: Latest just published simulation confirms large effect overestimates of trials stopped early for benefit. Trials typical of…