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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation
|
|---|---|
| Published in |
Molecular Neurodegeneration, April 2013
|
| DOI | 10.1186/1750-1326-8-12 |
| Pubmed ID | |
| Authors |
Vladimir L Buchman, Johnathan Cooper-Knock, Natalie Connor-Robson, Adrian Higginbottom, Janine Kirby, Olga D Razinskaya, Natalia Ninkina, Pamela J Shaw |
| Abstract |
Sizing of GGGGCC hexanucleotide repeat expansions within the C9ORF72 locus, which account for approximately 10% of all amyotrophic lateral sclerosis (ALS) cases, is urgently required to answer fundamental questions about mechanisms of pathogenesis in this important genetic variant. Currently employed PCR protocols are limited to discrimination between the presence and absence of a modified allele with more than 30 copies of the repeat, while Southern hybridisation-based methods are confounded by the somatic heterogeneity commonly present in blood samples, which might cause false-negative or ambiguous results. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Canada | 1 | 1% |
| Austria | 1 | 1% |
| Unknown | 97 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 21% |
| Researcher | 18 | 18% |
| Student > Bachelor | 12 | 12% |
| Student > Master | 10 | 10% |
| Student > Postgraduate | 6 | 6% |
| Other | 18 | 18% |
| Unknown | 15 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 25% |
| Biochemistry, Genetics and Molecular Biology | 19 | 19% |
| Neuroscience | 18 | 18% |
| Medicine and Dentistry | 13 | 13% |
| Psychology | 2 | 2% |
| Other | 4 | 4% |
| Unknown | 19 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2013.
All research outputs
#19,944,994
of 25,374,647 outputs
Outputs from Molecular Neurodegeneration
#890
of 977 outputs
Outputs of similar age
#156,212
of 212,292 outputs
Outputs of similar age from Molecular Neurodegeneration
#3
of 5 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 977 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.6. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 212,292 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.