Title |
The cryptochromes
|
---|---|
Published in |
Genome Biology, April 2005
|
DOI | 10.1186/gb-2005-6-5-220 |
Pubmed ID | |
Authors |
Chentao Lin, Takeshi Todo |
Abstract |
Cryptochromes are photoreceptors that regulate entrainment by light of the circadian clock in plants and animals. They also act as integral parts of the central circadian oscillator in animal brains and as receptors controlling photomorphogenesis in response to blue or ultraviolet (UV-A) light in plants. Cryptochromes are probably the evolutionary descendents of DNA photolyases, which are light-activated DNA-repair enzymes, and are classified into three groups -- plant cryptochromes, animal cryptochromes, and CRY-DASH proteins. Cryptochromes and photolyases have similar three-dimensional structures, characterized by an alpha/beta domain and a helical domain. The structure also includes a chromophore, flavin adenine dinucleotide (FAD). The FAD-access cavity of the helical domain is the catalytic site of photolyases, and it is predicted also to be important in the mechanism of cryptochromes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Russia | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | <1% |
Germany | 3 | <1% |
France | 1 | <1% |
Norway | 1 | <1% |
Brazil | 1 | <1% |
South Africa | 1 | <1% |
Hungary | 1 | <1% |
United Kingdom | 1 | <1% |
Canada | 1 | <1% |
Other | 6 | 1% |
Unknown | 413 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 91 | 21% |
Researcher | 65 | 15% |
Student > Bachelor | 62 | 14% |
Student > Master | 44 | 10% |
Student > Doctoral Student | 26 | 6% |
Other | 59 | 14% |
Unknown | 85 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 147 | 34% |
Biochemistry, Genetics and Molecular Biology | 97 | 22% |
Chemistry | 34 | 8% |
Neuroscience | 16 | 4% |
Medicine and Dentistry | 9 | 2% |
Other | 34 | 8% |
Unknown | 95 | 22% |