↓ Skip to main content

Characteristics and outcomes of cryptococcal meningitis in HIV seronegative children in Beijing, China, 2002–2013

Overview of attention for article published in BMC Infectious Diseases, November 2016
Altmetric Badge

Mentioned by

twitter
2 X users

Citations

dimensions_citation
25 Dimensions

Readers on

mendeley
51 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Characteristics and outcomes of cryptococcal meningitis in HIV seronegative children in Beijing, China, 2002–2013
Published in
BMC Infectious Diseases, November 2016
DOI 10.1186/s12879-016-1964-6
Pubmed ID
Authors

Ling-yun Guo, Lin-lin Liu, Yue Liu, Tian-ming Chen, Shao-ying Li, Yong-hong Yang, Gang Liu

Abstract

Data regarding HIV-seronegative pediatric patients with cryptococcal meningitis (CM) have been very limited. We retrospectively reviewed non-HIV-infected in patients with CM from January 2002 through December 2013 in Beijing Children's Hospital. Records of the all patients were obtained and compared. The 34 children had a median age of 5.6 years. Most of the patients were male (67.6 %). Only 23.5 % of the cases had identifiable underlying diseases. The sensitivity of the CSF cryptococcal antigen, India ink smear and CSF culture in our study were 81.5, 85.3 and 82.4 %, respectively. And the sensitivity of combinations of these tests was 91.2 %. Out of the 34 patients, 16 (47.1 %) had other organs involvement in addition to the brain. The main abnormal features via magnetic resonance imaging (MRI) were Virchow-Robin space dilatation (44.4 %), hydrocephalus (38.9 %), gelatinous pseudocysts (33.3 %), brain atrophy (33.3 %), meningeal enhancement (27.8 %) and local lesions (27.8 %). In total, 64.7 % of the patients were successfully treated at discharge, whereas treatment failed in 35.3 % of the patients. Cryptococcal meningitis is an infrequent disease with a high fatality rate in children in China. The majority of patients were apparently healthy. Clinicians should consider cryptococcal infection as a potential pathogen of pediatric meningitis. Cryptococcal antigen, India ink smear and culture tests are recommended for diagnosis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 20%
Researcher 8 16%
Student > Master 6 12%
Other 4 8%
Student > Ph. D. Student 4 8%
Other 7 14%
Unknown 12 24%
Readers by discipline Count As %
Medicine and Dentistry 22 43%
Biochemistry, Genetics and Molecular Biology 6 12%
Immunology and Microbiology 4 8%
Mathematics 1 2%
Unspecified 1 2%
Other 3 6%
Unknown 14 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2016.
All research outputs
#18,482,034
of 22,901,818 outputs
Outputs from BMC Infectious Diseases
#5,621
of 7,692 outputs
Outputs of similar age
#235,226
of 311,297 outputs
Outputs of similar age from BMC Infectious Diseases
#148
of 232 outputs
Altmetric has tracked 22,901,818 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,692 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,297 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 232 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.