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Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet

Overview of attention for article published in BMC Biology, August 2009
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5 news outlets
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5 X users
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Title
Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet
Published in
BMC Biology, August 2009
DOI 10.1186/1741-7007-7-47
Pubmed ID
Authors

Vincent Corbel, Maria Stankiewicz, Cédric Pennetier, Didier Fournier, Jure Stojan, Emmanuelle Girard, Mitko Dimitrov, Jordi Molgó, Jean-Marc Hougard, Bruno Lapied

Abstract

N,N-Diethyl-3-methylbenzamide (deet) remains the gold standard for insect repellents. About 200 million people use it every year and over 8 billion doses have been applied over the past 50 years. Despite the widespread and increased interest in the use of deet in public health programmes, controversies remain concerning both the identification of its target sites at the olfactory system and its mechanism of toxicity in insects, mammals and humans. Here, we investigated the molecular target site for deet and the consequences of its interactions with carbamate insecticides on the cholinergic system.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 206 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
France 2 <1%
Ireland 1 <1%
Mexico 1 <1%
Egypt 1 <1%
Unknown 198 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 37 18%
Researcher 37 18%
Student > Master 26 13%
Student > Bachelor 20 10%
Student > Postgraduate 9 4%
Other 31 15%
Unknown 46 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 72 35%
Chemistry 14 7%
Environmental Science 13 6%
Neuroscience 13 6%
Medicine and Dentistry 11 5%
Other 33 16%
Unknown 50 24%