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HIV-1 Tat interaction with Dicer: requirement for RNA

Overview of attention for article published in Retrovirology: Research & Treatment, December 2006
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

blogs
1 blog
peer_reviews
1 peer review site

Citations

dimensions_citation
78 Dimensions

Readers on

mendeley
71 Mendeley
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Title
HIV-1 Tat interaction with Dicer: requirement for RNA
Published in
Retrovirology: Research & Treatment, December 2006
DOI 10.1186/1742-4690-3-95
Pubmed ID
Authors

Yamina Bennasser, Kuan-Teh Jeang

Abstract

Dicer is an RNase III which processes two classes of cellular small RNAs: the microRNAs (miRNA) and short interfering RNAs (siRNA). Previously, we observed that over-expressed HIV-1 Tat protein can suppress the processing of small RNAs inside cells. Here, we have investigated the requirements for Tat interaction with Dicer. We report that Tat-Dicer interaction depends on RNA, requires the helicase domain of Dicer, and is independent of Tat's transactivation domain.

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 7%
Netherlands 1 1%
Germany 1 1%
Canada 1 1%
Unknown 63 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 24 34%
Student > Ph. D. Student 16 23%
Student > Bachelor 8 11%
Student > Master 8 11%
Other 3 4%
Other 9 13%
Unknown 3 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 40 56%
Biochemistry, Genetics and Molecular Biology 12 17%
Immunology and Microbiology 5 7%
Medicine and Dentistry 5 7%
Computer Science 3 4%
Other 2 3%
Unknown 4 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 June 2015.
All research outputs
#831,650
of 5,181,074 outputs
Outputs from Retrovirology: Research & Treatment
#55
of 451 outputs
Outputs of similar age
#16,551
of 94,474 outputs
Outputs of similar age from Retrovirology: Research & Treatment
#4
of 24 outputs
Altmetric has tracked 5,181,074 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 451 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,474 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.