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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) – 1, Nesfatin-1 and anthropometric features in patients with Hashimoto’s thyroiditis: a randomized controlled trial
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|---|---|
| Published in |
BMC Complementary Medicine and Therapies, November 2016
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| DOI | 10.1186/s12906-016-1432-2 |
| Pubmed ID | |
| Authors |
Mahdieh Abbasalizad Farhangi, Parvin Dehghan, Siroos Tajmiri, Mehran Mesgari Abbasi |
| Abstract |
Hashimoto's thyroiditis is an autoimmune disorder and the most common cause of hypothyroidism. The use of Nigella sativa, a potent herbal medicine, continues to increase worldwide as an alternative treatment of several chronic diseases including hyperlipidemia, hypertension and type 2 diabetes mellitus (T2DM). The aim of the current study was to evaluate the effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) - 1, Nesfatin-1 and anthropometric features in patients with Hashimoto's thyroiditis. Forty patients with Hashimoto's thyroiditis, aged between 22 and 50 years old, participated in the trial and were randomly allocated into two groups of intervention and control receiving powdered Nigella sativa or placebo daily for 8 weeks. Changes in anthropometric variables, dietary intakes, thyroid status, serum VEGF and Nesfatin-1 concentrations after 8 weeks were measured. Treatment with Nigella sativa significantly reduced body weight and body mass index (BMI). Serum concentrations of thyroid stimulating hormone (TSH) and anti-thyroid peroxidase (anti-TPO) antibodies decreased while serum T3 concentrations increased in Nigella sativa-treated group after 8 weeks. There was a significant reduction in serum VEGF concentrations in intervention group. None of these changes had been observed in placebo treated group. In stepwise multiple regression model, changes in waist to hip ratio (WHR) and thyroid hormones were significant predictors of changes in serum VEGF and Nesgfatin-1 values in Nigella sativa treated group (P < 0.05). Our data showed a potent beneficial effect of powdered Nigella sativa in improving thyroid status and anthropometric variables in patients with Hashimoto's thyroiditis. Moreover, Nigella sativa significantly reduced serum VEGF concentrations in these patients. Considering observed health- promoting effect of this medicinal plant in ameliorating the disease severity, it can be regarded as a useful therapeutic approach in management of Hashimoto's thyroiditis. Iranian registry of clinical trials (registration number IRCT2015021719082N4 - Registered March-15-2015). |
X Demographics
The data shown below were collected from the profiles of 68 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 16% |
| South Africa | 3 | 4% |
| United Kingdom | 2 | 3% |
| Saudi Arabia | 2 | 3% |
| Australia | 2 | 3% |
| Ghana | 1 | 1% |
| Tanzania, United Republic of | 1 | 1% |
| Italy | 1 | 1% |
| France | 1 | 1% |
| Other | 5 | 7% |
| Unknown | 39 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 54 | 79% |
| Practitioners (doctors, other healthcare professionals) | 12 | 18% |
| Scientists | 2 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 239 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 239 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 51 | 21% |
| Student > Doctoral Student | 23 | 10% |
| Student > Master | 18 | 8% |
| Researcher | 17 | 7% |
| Student > Ph. D. Student | 15 | 6% |
| Other | 34 | 14% |
| Unknown | 81 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 62 | 26% |
| Nursing and Health Professions | 27 | 11% |
| Biochemistry, Genetics and Molecular Biology | 15 | 6% |
| Agricultural and Biological Sciences | 11 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 11 | 5% |
| Other | 27 | 11% |
| Unknown | 86 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 301. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 February 2024.
All research outputs
#116,715
of 25,698,912 outputs
Outputs from BMC Complementary Medicine and Therapies
#19
of 3,987 outputs
Outputs of similar age
#2,174
of 289,432 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#1
of 62 outputs
Altmetric has tracked 25,698,912 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,987 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,432 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.