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Mendeley readers
| Title |
Synthesis and crystal structures of 5'-phenylspiro[indoline-3, 2'-pyrrolidin]-2-one derivatives
|
|---|---|
| Published in |
BMC Chemistry, July 2011
|
| DOI | 10.1186/1752-153x-5-45 |
| Pubmed ID | |
| Authors |
Jeyaperumal Kalyana Sundar, Stephen Michael Rajesh, Jeyaraman Sivamani, Subbu Perumal, Subramanian Natarajan |
| Abstract |
The spiro- indole-pyrrolidine ring system is a frequently encountered structural motif in many biologically important and pharmacologically relevant alkaloids. The derivatives of spirooxindole ring systems are used as antimicrobial, antitumour agents and as inhibitors of the human NKI receptor besides being found in a number of alkaloids like horsifiline, spirotryprostatin and (+) elacomine. The recently discovered small-molecule MDM2 inhibitor MI-219 and its analogues are in advanced preclinical development as cancer therapeutics. |
Mendeley readers
The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | 8% |
| Unknown | 23 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 44% |
| Researcher | 7 | 28% |
| Professor | 2 | 8% |
| Student > Doctoral Student | 1 | 4% |
| Professor > Associate Professor | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 2 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 16 | 64% |
| Physics and Astronomy | 6 | 24% |
| Unknown | 3 | 12% |