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Low level β-lactamase production in methicillin-resistant staphylococcus aureus strains with β-lactam antibiotics-induced vancomycin resistance

Overview of attention for article published in BMC Microbiology, May 2012
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29 Mendeley
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Title
Low level β-lactamase production in methicillin-resistant staphylococcus aureus strains with β-lactam antibiotics-induced vancomycin resistance
Published in
BMC Microbiology, May 2012
DOI 10.1186/1471-2180-12-69
Pubmed ID
Authors

Yuriko Hirao, Yurika Ikeda-Dantsuji, Hidehito Matsui, Masaki Yoshida, Seiji Hori, Keisuke Sunakawa, Taiji Nakae, Hideaki Hanaki

Abstract

A class of methicillin-resistant Staphylococcus aureus (MRSA) shows resistance to vancomycin only in the presence of ß-lactam antibiotics (BIVR). This type of vancomycin resistance is mainly attributable to the rapid depletion of free vancomycin in the presence of ß-lactam antibiotics. This means that ß-lactam antibiotics remain active or intact in BIVR culture, although most MRSA cells are assumed to produce ß-lactamase. We hypothesised that the BIVR cells either did not harbour the ß-lactamase gene, blaZ, or the gene was quiescent. We tested this hypothesis by determining ß-lactamase activity and conducting PCR amplification of blaZ.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
India 1 3%
Unknown 27 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 17%
Student > Postgraduate 4 14%
Student > Doctoral Student 3 10%
Student > Bachelor 3 10%
Student > Master 3 10%
Other 6 21%
Unknown 5 17%
Readers by discipline Count As %
Medicine and Dentistry 10 34%
Agricultural and Biological Sciences 5 17%
Immunology and Microbiology 3 10%
Biochemistry, Genetics and Molecular Biology 2 7%
Neuroscience 1 3%
Other 0 0%
Unknown 8 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 November 2019.
All research outputs
#12,583,769
of 22,707,247 outputs
Outputs from BMC Microbiology
#1,103
of 3,171 outputs
Outputs of similar age
#86,368
of 163,519 outputs
Outputs of similar age from BMC Microbiology
#12
of 22 outputs
Altmetric has tracked 22,707,247 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,171 research outputs from this source. They receive a mean Attention Score of 4.1. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,519 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.