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Role of astrocytes in manganese mediated neurotoxicity

Overview of attention for article published in BMC Pharmacology and Toxicology, April 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#31 of 279)
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

blogs
1 blog
twitter
5 tweeters

Citations

dimensions_citation
72 Dimensions

Readers on

mendeley
76 Mendeley
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Title
Role of astrocytes in manganese mediated neurotoxicity
Published in
BMC Pharmacology and Toxicology, April 2013
DOI 10.1186/2050-6511-14-23
Pubmed ID
Authors

Marta Sidoryk-Wegrzynowicz, Michael Aschner

Abstract

Astrocytes are responsible for numerous aspects of metabolic support, nutrition, control of the ion and neurotransmitter environment in central nervous system (CNS). Failure by astrocytes to support essential neuronal metabolic requirements plays a fundamental role in the pathogenesis of brain injury and the ensuing neuronal death. Astrocyte-neuron interactions play a central role in brain homeostasis, in particular via neurotransmitter recycling functions. Disruption of the glutamine (Gln)/glutamate (Glu) -γ-aminobutyric acid (GABA) cycle (GGC) between astrocytes and neurons contributes to changes in Glu-ergic and/or GABA-ergic transmission, and is associated with several neuropathological conditions, including manganese (Mn) toxicity. In this review, we discuss recent advances in support of the important roles for astrocytes in normal as well as neuropathological conditions primarily those caused by exposure to Mn.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 2 3%
United States 2 3%
United Kingdom 1 1%
Brazil 1 1%
Slovenia 1 1%
France 1 1%
Poland 1 1%
Unknown 67 88%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 25%
Student > Master 14 18%
Researcher 11 14%
Professor > Associate Professor 6 8%
Student > Bachelor 4 5%
Other 14 18%
Unknown 8 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 25%
Neuroscience 14 18%
Medicine and Dentistry 11 14%
Biochemistry, Genetics and Molecular Biology 7 9%
Pharmacology, Toxicology and Pharmaceutical Science 5 7%
Other 7 9%
Unknown 13 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 October 2018.
All research outputs
#1,495,073
of 13,657,732 outputs
Outputs from BMC Pharmacology and Toxicology
#31
of 279 outputs
Outputs of similar age
#17,800
of 149,857 outputs
Outputs of similar age from BMC Pharmacology and Toxicology
#1
of 5 outputs
Altmetric has tracked 13,657,732 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 279 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 149,857 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them