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An optimized algorithm for detecting and annotating regional differential methylation

Overview of attention for article published in BMC Bioinformatics, April 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

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6 X users
facebook
1 Facebook page
wikipedia
1 Wikipedia page

Citations

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114 Dimensions

Readers on

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160 Mendeley
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Title
An optimized algorithm for detecting and annotating regional differential methylation
Published in
BMC Bioinformatics, April 2013
DOI 10.1186/1471-2105-14-s5-s10
Pubmed ID
Authors

Sheng Li, Francine E Garrett-Bakelman, Altuna Akalin, Paul Zumbo, Ross Levine, Bik L To, Ian D Lewis, Anna L Brown, Richard J D'Andrea, Ari Melnick, Christopher E Mason

Abstract

DNA methylation profiling reveals important differentially methylated regions (DMRs) of the genome that are altered during development or that are perturbed by disease. To date, few programs exist for regional analysis of enriched or whole-genome bisulfate conversion sequencing data, even though such data are increasingly common. Here, we describe an open-source, optimized method for determining empirically based DMRs (eDMR) from high-throughput sequence data that is applicable to enriched whole-genome methylation profiling datasets, as well as other globally enriched epigenetic modification data.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 160 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 10 6%
Germany 2 1%
India 1 <1%
Sweden 1 <1%
Japan 1 <1%
Russia 1 <1%
Unknown 144 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 45 28%
Student > Ph. D. Student 41 26%
Student > Master 13 8%
Professor > Associate Professor 11 7%
Student > Bachelor 8 5%
Other 27 17%
Unknown 15 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 70 44%
Biochemistry, Genetics and Molecular Biology 29 18%
Computer Science 13 8%
Medicine and Dentistry 8 5%
Engineering 5 3%
Other 16 10%
Unknown 19 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2020.
All research outputs
#4,581,306
of 22,708,120 outputs
Outputs from BMC Bioinformatics
#1,760
of 7,256 outputs
Outputs of similar age
#39,639
of 199,476 outputs
Outputs of similar age from BMC Bioinformatics
#32
of 135 outputs
Altmetric has tracked 22,708,120 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,256 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,476 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 135 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.