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Mendeley readers
Attention Score in Context
| Title |
The Contribution of Spinal Glial Cells to Chronic Pain Behaviour in the Monosodium Iodoacetate Model of Osteoarthritic Pain
|
|---|---|
| Published in |
Molecular Pain, January 2011
|
| DOI | 10.1186/1744-8069-7-88 |
| Pubmed ID | |
| Authors |
Devi Rani Sagar, James J Burston, Gareth J Hathway, Stephen G Woodhams, Richard G Pearson, Andrew J Bennett, David A Kendall, Brigitte E Scammell, Victoria Chapman |
| Abstract |
Clinical studies of osteoarthritis (OA) suggest central sensitization may contribute to the chronic pain experienced. This preclinical study used the monosodium iodoacetate (MIA) model of OA joint pain to investigate the potential contribution of spinal sensitization, in particular spinal glial cell activation, to pain behaviour in this model. Experimental OA was induced in the rat by the intra-articular injection of MIA and pain behaviour (change in weight bearing and distal allodynia) was assessed. Spinal cord microglia (Iba1 staining) and astrocyte (GFAP immunofluorescence) activation were measured at 7, 14 and 28 days post MIA-treatment. The effects of two known inhibitors of glial activation, nimesulide and minocycline, on pain behaviour and activation of microglia and astrocytes were assessed. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | <1% |
| Unknown | 133 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 19% |
| Researcher | 20 | 15% |
| Student > Bachelor | 18 | 13% |
| Student > Master | 15 | 11% |
| Other | 7 | 5% |
| Other | 22 | 16% |
| Unknown | 27 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 31 | 23% |
| Agricultural and Biological Sciences | 21 | 16% |
| Medicine and Dentistry | 20 | 15% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 5% |
| Veterinary Science and Veterinary Medicine | 6 | 4% |
| Other | 20 | 15% |
| Unknown | 29 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2013.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from Molecular Pain
#477
of 669 outputs
Outputs of similar age
#170,829
of 190,479 outputs
Outputs of similar age from Molecular Pain
#29
of 36 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 190,479 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.