RT @drmattrpaul: In 2020, I implicated PAQR8 gain in metastases based solely on genomic assays. Since then, Saisai Chen just published her…
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In 2020, I implicated PAQR8 gain in metastases based solely on genomic assays. Since then, Saisai Chen just published her work in our lab which extensively shows that PAQR8 gain promotes breast cancer recurrence and treatment resistance. I'm ecstatic! http
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Dr. Lewis Chodosh's team at @Penn_CBIO shows that PAQR8 is necessary for efficient #MammaryTumor recurrence in mice and spontaneously upregulated and copy number gained in recurrent tumors following therapy in multiple mouse models. 🐭 @PennMedicine 🔓 http