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jMOSAiCS: joint analysis of multiple ChIP-seq datasets

Overview of attention for article published in Genome Biology, April 2013
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (75th percentile)

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Citations

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124 Mendeley
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9 CiteULike
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Title
jMOSAiCS: joint analysis of multiple ChIP-seq datasets
Published in
Genome Biology, April 2013
DOI 10.1186/gb-2013-14-4-r38
Pubmed ID
Authors

Xin Zeng, Rajendran Sanalkumar, Emery H Bresnick, Hongda Li, Qiang Chang, Sündüz Keleş

Abstract

The ChIP-seq technique enables genome-wide mapping of in vivo protein-DNA interactions and chromatin states. Current analytical approaches for ChIP-seq analysis are largely geared towards single-sample investigations, and have limited applicability in comparative settings that aim to identify combinatorial patterns of enrichment across multiple datasets. We describe a novel probabilistic method, jMOSAiCS, for jointly analyzing multiple ChIP-seq datasets. We demonstrate its usefulness with a wide range of data-driven computational experiments and with a case study of histone modifications on GATA1-occupied segments during erythroid differentiation. jMOSAiCS is open source software and can be downloaded from Bioconductor 1.

X Demographics

X Demographics

The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 4%
France 2 2%
United Kingdom 2 2%
Netherlands 1 <1%
Germany 1 <1%
Australia 1 <1%
China 1 <1%
Canada 1 <1%
Unknown 110 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 35 28%
Student > Ph. D. Student 34 27%
Student > Master 14 11%
Professor > Associate Professor 10 8%
Student > Bachelor 7 6%
Other 17 14%
Unknown 7 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 68 55%
Biochemistry, Genetics and Molecular Biology 16 13%
Computer Science 16 13%
Mathematics 7 6%
Immunology and Microbiology 2 2%
Other 6 5%
Unknown 9 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 November 2013.
All research outputs
#6,354,466
of 25,736,439 outputs
Outputs from Genome Biology
#3,037
of 4,509 outputs
Outputs of similar age
#49,291
of 205,072 outputs
Outputs of similar age from Genome Biology
#38
of 49 outputs
Altmetric has tracked 25,736,439 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,509 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 205,072 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.