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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Effects of selective serotonin reuptake inhibitor treatment on plasma oxytocin and cortisol in major depressive disorder
|
|---|---|
| Published in |
BMC Psychiatry, April 2013
|
| DOI | 10.1186/1471-244x-13-124 |
| Pubmed ID | |
| Authors |
Charlotte Keating, Tye Dawood, David A Barton, Gavin W Lambert, Alan J Tilbrook |
| Abstract |
Oxytocin is known for its capacity to facilitate social bonding, reduce anxiety and for its actions on the stress hypothalamopituitary adrenal (HPA) axis. Since oxytocin can physiologically suppress activity of the HPA axis, clinical applications of this neuropeptide have been proposed in conditions where the function of the HPA axis is dysregulated. One such condition is major depressive disorder (MDD). Dysregulation of the HPA system is the most prominent endocrine change seen with MDD, and normalizing the HPA axis is one of the major targets of recent treatments. The potential clinical application of oxytocin in MDD requires improved understanding of its relationship to the symptoms and underlying pathophysiology of MDD. Previous research has investigated potential correlations between oxytocin and symptoms of MDD, including a link between oxytocin and treatment related symptom reduction. The outcomes of studies investigating whether antidepressive treatment (pharmacological and non-pharmacological) influences oxytocin concentrations in MDD, have produced conflicting outcomes. These outcomes suggest the need for an investigation of the influence of a single treatment class on oxytocin concentrations, to determine whether there is a relationship between oxytocin, the HPA axis (e.g., oxytocin and cortisol) and MDD. Our objective was to measure oxytocin and cortisol in patients with MDD before and following treatment with selective serotonin reuptake inhibitors, SSRI. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 13% |
| Mexico | 1 | 13% |
| United States | 1 | 13% |
| Egypt | 1 | 13% |
| Unknown | 4 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 75% |
| Practitioners (doctors, other healthcare professionals) | 2 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Russia | 1 | <1% |
| Australia | 1 | <1% |
| Switzerland | 1 | <1% |
| Unknown | 111 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 17% |
| Student > Bachelor | 18 | 16% |
| Student > Master | 17 | 15% |
| Researcher | 16 | 14% |
| Other | 7 | 6% |
| Other | 18 | 16% |
| Unknown | 19 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 31 | 27% |
| Medicine and Dentistry | 27 | 23% |
| Agricultural and Biological Sciences | 11 | 10% |
| Nursing and Health Professions | 4 | 3% |
| Biochemistry, Genetics and Molecular Biology | 4 | 3% |
| Other | 14 | 12% |
| Unknown | 24 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2013.
All research outputs
#6,053,255
of 23,881,329 outputs
Outputs from BMC Psychiatry
#2,143
of 4,939 outputs
Outputs of similar age
#48,502
of 194,583 outputs
Outputs of similar age from BMC Psychiatry
#34
of 81 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 4,939 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.9. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,583 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.